Pancreatic Beta-Cells

• R. Bertram, A. Sherman, L. S. Satin, (2007) Metabolic and electrical oscillations: partners in controlling pulsatile insulin secretion, American Journal of Physiology 293:E890-E900. pdf



• R. Bertram, L. S. Satin, M. G. Pedersen, D. S. Luciani, A. Sherman, (2007) Interaction of Glycolysis and Mitochondrial Respiration in Metabolic Oscillations of Pancreatic Islets, Biophysical Journal 92:1544-1555. pdf



• R. Bertram, M. G. Pedersen, D. S. Luciani, A. Sherman (2006) A Simplified Model for Mitochondrial ATP Production, Journal of Theoretical Biology 243:575-586. pdf



• C. S. Nunemaker, R. Bertram, A. Sherman, K. Tsaneva-Atanasova, C. R. Daniel, L. S. Satin (2006) Glucose Modulates Calcium Oscillations in Pancreatic Islets via Ionic and Glycolytic Mechanisms, Biophysical Journal 91:2082-2096. pdf



• K. Tsaneva-Atanasova, C. L. Zimliki, R. Bertram, A. Sherman (2006) Diffusion of Calcium and Metabolites in Pancreatic Islets: Killing Oscillations with a Pitchfork, Biophysical Journal 90:3434-3446. pdf



• C. S. Nunemaker, M. Zhang, D. H. Wasserman, O. P. McGuinness, A. C. Powers, R. Bertram, A. Sherman, and L. S. Satin (2005) Individual Mice Can Be Distinguished by the Period of Their Islet Calcium Oscillations: Is There an Intrinsic Islet Period That Is Imprinted In Vivo?, Diabetes 54:3517-3522. pdf



• R. Bertram and A. Sherman (2005) Negative Calcium Feedback: The Road from Chay-Keizer. Book chapter in Bursting: The Genesis of Rhythm in the Nervous System, edited by S. Coombes and P. Bressloff, World Scientific Press, pp. 19-48. Book



• A. Sherman and R. Bertram (2005) Integrative Modeling of the Pancreatic Beta-Cell. In Wiley Interscience Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics, part 3, Proteomics, M. Dunn (ed.), Section 3.8, Systems Biology, R. L. Winslow (ed.), John Wiley and Sons, Ltd., ISBN: 0-470-84974-6. pdf



• M. G. Pedersen, R. Bertram, and A. Sherman (2005) Intra- and Inter-Islet Synchronization of Metabolically Driven Insulin Secretion. Biophysical Journal 89:107-119. pdf



• R. Bertram and A. Sherman (2004) Filtering of Calcium Transients by the Endoplasmic Reticulum in Pancreatic Beta-Cells. Biophysical Journal 87:3775-3785. pdf



• R. Bertram, L. Satin, M. Zhang, P. Smolen, and A. Sherman (2004) Calcium and Glycolysis Mediate Multiple Bursting Modes in Pancreatic Islets. Biophysical Journal 87:3074-3087. pdf



• R. Bertram and A. Sherman (2004) A Calcium-Based Phantom Bursting Model for Pancreatic Islets. Bulletin of Mathematical Biology 66: 1313-1344. pdf



• K. Wierschem and R. Bertram (2004) Complex Bursting in Pancreatic Islets: A Potential Glycolytic Mechanism. Journal of Theoretical Biology 228: 513-521. pdf



• M. Zhang, P. Goforth, R. Bertram, A. Sherman, L. Satin (2003) The Calcium Dynamics of Isolated Mouse Beta-Cells and Islets: Implications for Mathematical Models. Biophysical Journal 84:2852-2870. pdf



• R. Bertram, K. Wierschem, M. Zhang, P. Goforth, A. Sherman, L. S. Satin (2002) Phantom Bursting in Pancreatic Islets: A Potential Role for Insulin Feedback. In Recent Research Developments in Biophysics, S. G. Pandalai (Ed.), Transworld Research Network Publishers, 1: 31-51.



• P. B. Goforth, R. Bertram, F. A. Khan, M. Zhang, A. Sherman, L. S. Satin (2002) Calcium-Activated Potassium Channels of Mouse Beta-Cells are Controlled by Both Store and Cytoplasmic Calcium: Experimental and Theoretical Studies. Journal of General Physiology 120: 307-322. ps.gz



• Richard Bertram, Joseph Previte, Arthur Sherman, Tracie A. Kinard, and Leslie S. Satin (2000) The Phantom Burster Model for Pancreatic Beta-Cells. Biophysical Journal 79:2880-2892. pdf



• Richard Bertram and Arthur Sherman (2000) Dynamical Complexity and Temporal Plasticity in Pancreatic Beta-Cells. Journal of Biosciences 25:197-209.



• Richard Bertram and Mark Pernarowski (1998) Glucose Diffusion in Pancreatic Islets of Langerhans. Biophysical Journal 74:1722-1731. pdf



• David Mears, Norman F. Sheppard, Illani Atwater, Eduardo Rojas, Richard Bertram, and Arthur Sherman (1997) Evidence That Calcium Release-Activated Current Mediates the Biphasic Electrical Activity of Mouse Pancreatic Beta-Cells. Journal of Membrane Biology 155:47-60. pdf



• Richard Bertram, Paul Smolen, Arthur Sherman, David Mears, Illani Atwater, Franz Martin, and Bernat Soria (1995) A Role for Calcium Release-Activated Current (CRAC) in Cholinergic Modulation of Electrical Activity in Pancreatic Beta-Cells. Biophysical Journal 68:2323-2332. pdf