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MICHAEL BROWN

Ribosomal RNA Secondary Structure Analysis Using Stochastic Context Free Grammars

Progress in the last three months has occurred in two main areas. I now have new experimental results.

I was able to correct several small errors in the code that does secondary structure prediction. I now have secondary structure predictions for ALL bacterial small subunit ribosomal RNA sequences in the RDP database that have complete sequences. I am working to finish a document describing these new results.

Secondly, I have been working with Support Vector Machines (SVMs) to do classification. The initial work uses SVMs to do gene microarray expression data classification. I hope to extend this work to use SCFG features of small subunit ribosomal RNA sequences in a SVM classifier that does phylogenetic classification. A paper describing these results will be available soon.

 
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