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Natalia Toporikova

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MATHEMATICS COLLOQUIUM

Speaker: Natalia Toporikova
Title: One Cell, Two Bursting Mechanisms: In Vivo Conditions Change the In Vitro Burst in Pyramidal Cells of the Electro Lateral Lobe (ELL) of Electric Fish
Affiliation: McGill University
Date: Friday, September 19, 2008
Place and Time: Room 101, Love Building, 3:35-4:30 pm
Refreshments: Room 204, Love Building, 3:00 pm

Abstract. The intrinsic mechanisms underlying burst generation in vitro are generally well understood. However, how these mechanisms are implemented under in vivo conditions is still not clear. Pyramidal cells within the Electro Lateral Lobe of the electric fish have a well defined burst mechanism in vitro which is based on a somato-dendritic interaction. Surprisingly, in vivo recordings from these cells do not show any of the characteristics associated with bursting found in vitro. We propose a computational model that can explain these differences.



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Last modified: Monday August 25th, 2008