A semi-analytical method is proposed for calculating the response of a linear cascade with spanwise mean flow subject to oblique gusts. It is developed based on the boundary value problems defined by Lloyd and Peake (AIAA paper 2008-2840). A gust strength parameter is introduced and the correct three-dimensional (3-D) response is obtained. The classic similarity rules are extended; the approach can be used to extend any 2-D methods to account for oblique gusts and 3-D mean flows. It is validated against analytical approximations for single-airfoil and cascade responses. The method is used to investigate the effect of gust angle on the unsteady lift and the sound field. It is found that as increases, the 2-D equivalent response varies slightly. However, the 3-D lift is amplified by factor , and the spanwise phase variation increases. Cascade effects are also studied. The inter-blade phase angle (IBPA) is important even for very low solidity. As the solidity increases, the chordwise distribution of lift is no longer leading-edge dominant. Cascade effects are small only when the cascade blade count is lower than a limit. A statistics analysis reveals that Mach number is the most important parameter for determining this blade count limit, and frequency is the least important.