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Colin Studholme


Speaker: Colin Studholme
Title: Human Fetal Brain Mapping
Affiliation: University of California, San Francisco
Date: Friday, February 11, 2011
Place and Time: Room 101, Love Building, 3:35-4:30 pm
Refreshments: Room 204, Love Building, 3:00 pm

Abstract. This talk will describe the recent development of techniques that allow the formation and analysis of high resolution 3D MR images of the developing human fetal brain in utero. Different approaches that form 3D images from fast multi-slice 2D imaging studies will be described. These combine motion scattered multi slice clinical imaging studies to increase signal to noise and spatial resolution. Approaches to the problem of automated segmentation of developing brain tissues from reconstructed 3D images will then be then be reviewed. These are aimed at quantifying both developed and transient tissue structures present in fetal brain anatomy at different ages. Finally, methodology to map the spatial variation in tissue volume growth rates and surface folding will be covered. Results will be presented on studies mapping the emergence of primary sulci in utero and emergence of local and regional asymmetries in the brain.