Bhargav Ram Karamched

Bhargav Ram Karamched

Biomathematics, Biophysics, and Bioengineering

I am an Assistant Professor at Florida State University in the Department of Mathematics and the Institute of Molecular Biophysics. I am interested in a number of topics in applied mathematics, specifically involving applications of the theory of dynamical systems, partial and stochastic differential equations, and nonequilibrium statistical physics to problems in cell biology, synthetic biology, physiology, collective behavior, and decision making.

Contact:
1017 Academic Way, Room 217
Tallahassee, FL, 32306-4510
Email: bkaramched@fsu.edu
Affiliations:
Department of Mathematics
Institute of Molecular Biophysics
Program in Neuroscience
FSU Mathematics Biodynamics Group

Current Research Focus

  • Symmetry-breaking in Nascent Neurons
  • Virotherapy for Bacterial Infections
  • Spatiotemporal Dynamics in Bacterial Consortia
  • Emergent Order in Foraging Ants
  • Mechanisms of Olfaction
  • Social Decision-Making
  • Mechanisms Underlying Chaos in Physiological Systems
  • Theory and Applications of Stochastic Delays in Biological Systems

Before coming to FSU I was a postdoctoral fellow at the University of Houston and Rice University, collaborating with Professors Kresimir Josic, Matthew Bennett, and Will Ott. I obtained my Ph.D. in Mathematics from the University of Utah under the supervision of Professor Paul Bressloff in 2017. Prior to that, I obtained B.S. degrees in Mathematics and Biochemistry from the University of Oklahoma in 2012.

Publications

Biomolecular Feedback Systems

3. C. J. Ryzowicz, R. Bertram, B. R. Karamched. Dynamic Homeostasis in Relaxation and Bursting Oscillations. SIAM Journal on the Life Sciences 1:1, 1-29 (2026).
2. C. J. Ryzowicz, R. Bertram, B. R. Karamched. Oscillations in Delayed Positive Feedback Systems. Physical Chemistry Chemical Physics. 26, 24861-24869. (2024).
1. B. R. Karamched and C. E. Miles. Stochastic Switching of Delayed Feedback Suppresses Oscillations in Genetic Regulatory Systems. Journal of Royal Society Interface. 20: 20230059 Preprint. (2023).

Cancer

1. I. Kemler, B. R. Karamched, C. Neuhauser, D. Dingli. Quantitative Imaging and Dynamics of Tumor Therapy with Viruses. The FEBS Journal. https://doi.org/10.1111/febs.16102. (2021).

Cellular Neuroscience

6. D. Wharton, L. M. Leong, N. Subramaniam, D. A. Storace, B. R. Karamched, R. Bertram. Analysis of a Simple Model for Local and Lateral Inhibition in the Olfactory Bulb. Submitted.
5. L. M. Leong, D. Wharton, N. Subramaniam, B. R. Karamched, R. Bertram, and D. A. Storace. Evidence that Interglomerular Inhibition Generates Non-Monotonic Concentration-Response Relationships in Mitral/Tufted Glomeruli in the Mouse Olfactory Bulb. Journal of Physiology.
4. F. Bai, R. Bertram, and B. R. Karamched. A Mathematical Study of the Efficacy of Possible Negative Feedback Pathways Involved in Neuronal Polarization. Journal of Theoretical Biology. 111561. (2023).
3. F. Bai, R. Bertram, and B. R. Karamched. A Closed-Loop Multi-Scale Model for Intrinsic Frequency-Dependent Regulation of Axonal Growth. Mathematical Biosciences. 344: 108768 (2022).
2. P. C. Bressloff and B. R. Karamched. A Frequency-Dependent Decoding Mechanism for Axonal Length Sensing. Front. Cell. Neurosci. 9:281. (2015).
1. B. R. Karamched and P. C. Bressloff. A Delayed Feedback Model of Axonal Length Sensing. Biophys. J. 108 2408-2419 (2015).

Ecology

2. S. Guha, S. D. Ryan, and B. R. Karamched. Macroscopic Dominance from Microscopic Extremes: Symmetry Breaking in Spatial Competition. Submitted.
1. S. Hartman, S. D. Ryan, and B. R. Karamched. Walk this Way: Modeling Foraging Ant Dynamics in Multiple Food Source Environments. Journal of Mathematical Biology. 89, 41 (2024).

Epidemiology

1. Z. Dere, N. G. Cogan, B. R. Karamched. Optimal Control Strategies for Mitigating Antibiotic Resistance: Integrating Virus Dynamics for Enhanced Intervention Design. Mathematical Biosciences. 386: 109464 (2025).

Mathematical Theory

2. B. R. Karamched. Entropic Collapse and Extreme First Passage Times in Discrete Ballistic Transport. Submitted.
1. B. R. Karamched, J. Schmidt, and D. Murrugarra. Observability of Complex Systems via Conserved Quantities. Physica D: Nonlinear Phenomena. 477: 134714. (2025).

Physiology

2. B. R. Karamched, G. Hripcsak, R. L. Leibel, D. Albers, and W. Ott. Delay-Induced Uncertainty in the Glucose-Insulin System: Pathogenicity for Obesity and Type-2 Diabetes Mellitus. Frontiers in Physiology. 13:936101 (2022).
1. B. R. Karamched, G. Hripcsak, D. J. Albers, and W. Ott. Delay-Induced Uncertainty in a Paradigmatic Glucose-Insulin Model. Chaos 31 023142. Preprint. (2021).

Protein Trafficking

5. M. V. Ciocanel and B. R. Karamched. Both Sides Now: Modeling Motor Regulation of Microtubule Length at Both Ends. Physical Biology. 23 036001 (2026).
4. P. C. Bressloff and B. R. Karamched. Doubly Stochastic Poisson Model of Flagellar Length Control. SIAM J. Appl. Math 78(2), 719-741 (2018).
3. P. C. Bressloff, B. R. Karamched, S. D. Lawley, and E. Levien. Diffusive Transport in the Presence of Stochastically Gated Absorption. Physical Review E. 96 (2) (2017).
2. B. R. Karamched and P. C. Bressloff. Effects of Cell Geometry on Reversible Vesicular Delivery. J. Phys. A. 50 055601 (2017).
1. P. C. Bressloff and B. R. Karamched. A Model of Reversible Vesicular Transport with Exclusion. J. Phys. A. 49 345602 (2016).

Social Decision Making

4. S. Linn, S. D. Lawley, B. R. Karamched, Z. P. Kilpatrick, K. Josic. Fast decisions reflect biases, slow decisions do not. Physical Review E 110, 024305 (2024). Preprint.
3. M. Stickler, W. Ott, Z. P. Kilpatrick, K. Josic, and B. R. Karamched. Impact of Correlated Information on Pioneering Decisions. Physical Review Research. 5, 033020. (2023).
2. B. R. Karamched, M. Stickler, B. Lindner, Z. P. Kilpatrick, W. Ott, and K. Josic. Heterogeneity Improves Speed and Accuracy in Social Networks. Phys. Rev. Lett. 125, 218302 Preprint. (2020).
1. B. R. Karamched, S. Stolarczyk, Z. P. Kilpatrick, and K. Josic. Bayesian Evidence Accumulation on Social Networks. SIADS 19 (3) 1884-1919 Preprint (2020).

Synthetic Biology

5. V. L. DeVito and B. R. Karamched. Signed, Sealed, Delivered: A Generalizable Model for Probiotic Delivery and Metabolism in the Gut. npj Systems Biology 12, 48 (2026).
4. R. Godin, B. R. Karamched, S. D. Ryan. The Space Between Us: Modeling Spatial Heterogeneity in Synthetic Microbial Consortia Dynamics. Biophysical Reports. 100085. (2022).
3. J. J. Winkle, B. R. Karamched, M. R. Bennett, W. Ott, and K. Josic. Emergent Spatiotemporal Population Dynamics with Cell-Length Control of Synthetic Microbial Consortia. PLoS Comput Biol. 17(9): e1009381. https://doi.org/10.1371/journal.pcbi.1009381 Preprint. (2021).
2. B. R. Karamched, W. Ott, I. Timofeyev, M. R. Bennett, and K. Josic. Moran Model of Spatial Alignment in Microbial Colonies. Physica D: Nonlinear Phenomena. 395 1-6 Preprint (2019).
1. R. N. Alnahhas, J. J. Winkle, A. J. Hirning, B. R. Karamched, W. Ott, K. Josic, and M. R. Bennett. Spatiotemporal Dynamics of Synthetic Microbial Consortia in Microfluidic Devices. ACS Synthetic Biology 8 2051-2058 Preprint (2019).

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